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Pathogenesis of SARS-CoV-2 and important insights on its potent inhibitors remdesivir and chloroquine - A review
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The combination therapy including Remdesivir and chloroquine are exceptionally successful in the control of 2019-nCoV disease in vitro. Fundamental preliminaries of Remdesivir and chloroquine repurposing in the treatment of COVID-19 have been empowering, prompting a few new trials. In this review, pathogenesis of the SARS-CoV-2 and the potential mechanism of two potent inhibitors remdesivir and chloroquine as effective therapeutic agents against COVID-19 are described. |