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Seroprevalence of hepatitis B surface antigen (HBsAg) among patients at a tertiary care hospital in Mumbai, India

Hepatitis B virus (HBV) infection is a global public health problem. There is wide variation in seroprevalence of HBV infection. Majority of these infections are chronic and asymptomatic leading to complications like cirrhosis and hepatocellular carcinoma. Aim of the study is to determine seroprevalence of HBV among patients who were attending a tertiary care hospital at Mumbai and to study their demographic features. Patients attending outpatient Department and inpatient Department who were advised for HBsAg testing were included in the study. HBsAg was detected using the Enzyme linked immunosorbent assay (ELISA). Out of 21,782 patients who were screened for HBsAg, 529(2.42%) were positive. Among the positive cases, prevalence was highest in the age group of 31-45 years (37%). Seropositivity was higher in males (70.3%). Majority of these infections were asymptomatic (55.7%) and detected during routine screening for operative procedures, dialysis and antenatal care. Surveillance for seroprevalence of HBV is necessary for evaluating vaccination programs and other prevention and control efforts. Early diagnosis of HBV infection can prevent its spread and complications which results from chronic infection. | Seroprevalence of hepatitis B surface antigen HBsAg among patients at a tertiary care hospital in Mumbai India