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Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines

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Sirtuin 2 (SIRT2) is a member of the sirtuin family, nicotinamide adenine dinucleotide+ -dependent deacylases, which participates in modulation of cell cycle control, neurodegeneration, and tumorigenesis. SIRT2 expression increases in acute myeloid leukemia blasts. | Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines

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