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Ex vivo tissue slice culture system to measure drug-response rates of hepatic metastatic colorectal cancer

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The lack of predictive biomarkers or test systems contributes to high failure rates of systemic therapy in metastasized colorectal carcinoma, accounting for a still unfavorable prognosis. Here, we present an ex vivo functional assay to measure drug-response based on a tissue slice culture approach. | Ex vivo tissue slice culture system to measure drug-response rates of hepatic metastatic colorectal cancer