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Mutations within the quinolone resistance determining region in fluoroquinolone-resistant staphylococcus epidermidis recovered from different ocular isolates

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Staphylococcus epidermidis (S. epidermidis) is a common pathogen in ocular infection. Mutations contribute to drug resistance. We intended to identify mutations in genes within the quinolone resistance determining region (QRDR) of fluoroquinolone-resistant S. epidermidis ocular isolates and to study their phenotypic and genotypic correlation. A total of 50 phenotypically fluoroquinolones-resistant S. epidermidis isolates were studied. Fluoroquinolones susceptibility was evaluated by Kirby- Bauer disk diffusion method. | Mutations within the quinolone resistance determining region in fluoroquinolone-resistant staphylococcus epidermidis recovered from different ocular isolates

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Mutations within the quinolone resistance determining region in fluoroquinolone-resistant staphylococcus epidermidis recovered from different ocular isolates