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Suppression of myostatin stimulates regenerative potential of injured antigravitational soleus muscle in mice under unloading condition

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Effects of myostatin (MSTN)-suppression on the regeneration of injured skeletal muscle under unloading condition were investigated by using transgenic mice expressing a dominant-negative form of MSTN (MSTN-DN). Both MSTN-DN and wild-type (WT) mice were subjected to continuous hindlimb suspension (HS) for 6 weeks. | Suppression of myostatin stimulates regenerative potential of injured antigravitational soleus muscle in mice under unloading condition