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Effect of Plumbagin on growth inhibition and apoptosis of imatinib-resistant chronic myeloid leukemia
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Development of a new inhibitor of BCR-ABL tyrosine kinase is necessary for the treatment of chronic myeloid leukemia (CML) because of increasing resistance and tolerance to Imatinid efforts. Herein, we reported Plumbagin can significantly inhibit the growth of CML. | Effect of Plumbagin on growth inhibition and apoptosis of imatinib-resistant chronic myeloid leukemia