"Homologous repair" trang 1 - tải miễn phí từ tailieunhanh
Landscape of homologous recombination deficiencies in solid tumours: Analyses of two independent genomic datasets

Landscape of homologous recombination deficiencies in solid tumours: Analyses of two independent genomic datasets
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Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carriers of homologous recombination repair genes mutation in response or stable after olaparib treatment

Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carriers of homologous recombination repair genes mutation in response or stable after olaparib treatment
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Functional analyses of rare germline BRCA1 variants by transcriptional activation and homologous recombination repair assays

Functional analyses of rare germline BRCA1 variants by transcriptional activation and homologous recombination repair assays
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IMAGENE trial: Multicenter, proof-of-concept, phase II study evaluating the efcacy and safety of combination therapy of niraparib with PD-1 inhibitor in solid cancer patients with homologous recombination repair genes mutation

IMAGENE trial: Multicenter, proof-of-concept, phase II study evaluating the efcacy and safety of combination therapy of niraparib with PD-1 inhibitor in solid cancer patients with homologous recombination repair genes mutation
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LncRNA ANRIL promotes HR repair through regulating PARP1 expression by sponging miR-7-5p in lung cancer

LncRNA ANRIL promotes HR repair through regulating PARP1 expression by sponging miR-7-5p in lung cancer
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MiR-7-5p-mediated downregulation of PARP1 impacts DNA homologous recombination repair and resistance to doxorubicin in small cell lung cancer

MiR-7-5p-mediated downregulation of PARP1 impacts DNA homologous recombination repair and resistance to doxorubicin in small cell lung cancer
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Effective control of large deletions after double-strand breaks by homologydirected repair and dsODN insertion

Effective control of large deletions after double-strand breaks by homologydirected repair and dsODN insertion
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Báo cáo khoa học:

Báo cáo khoa học: " Inhibition of homologous recombination repair with Pentoxifylline targets G2 cells generated by radiotherapy and induces major enhancements of the toxicity of cisplatin and melphalan given after irradiation"
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Flp1 may function in the resolution of recombinant DNA intermediates

Flp1 may function in the resolution of recombinant DNA intermediates
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Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro
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Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands

Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands
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Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage

Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage
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Analysis of injury and growth behaviors of stressed bacillus subtilis spores using the double subculture method

Analysis of injury and growth behaviors of stressed bacillus subtilis spores using the double subculture method
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ATM depletion induces proteasomal degradation of FANCD2 and sensitizes neuroblastoma cells to PARP inhibitors

ATM depletion induces proteasomal degradation of FANCD2 and sensitizes neuroblastoma cells to PARP inhibitors
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Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells

Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in some brain tumour cells
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A phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA defective tumours: A study protocol

A phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA defective tumours: A study protocol
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