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Lecture Principles of biochemistry - Chapter 1: Introduction to biochemistry

After completing this chapter, students will be able to: Know what are the most abundant elements in biological systems; know the structures of the commonly occurring organic compounds, functional groups and linkages found in biochemical compounds; know the monomer, polymer and supramolecular structural relationships of lipids, proteins, nucleic acids, and carbohydrates; know the major differences between a prokaryotic and eukaryotic cell; know the major functions associated with the different organelles and cellular compartments of eukaryotic cells. | BCH 400/600 – Introductory Biochemistry Instructor: David Shintani Office: 311C Fleischmann Ag. Lab: 308 Fleischmann Ag. E-mail: shintani@unr.edu Phone: (775) 784-4631 Before BCH 400 After BCH 400 BCH 400 is heavy on content!!! Come to class!!!!!! Try not to fall behind!! Review lecture notes. http://www.ag.unr.edu/shintani/bch400-600/index.html Read book chapters. Principles of Biochemistry 4th Edition Principles of Biochemistry 3rd Edition Use tools to memorize Histidine? Study in groups Participate in the clicker system!!! 20 extra credit points!! Feel Free to see me! My office hours are Tuedays from 2:00 to 3:00 PM Or e-mail me for a private audience What is Biochemistry? Biochemistry = chemistry of life. Biochemists use physical and chemical principles to explain biology at the molecular level. Basic principles of biochemistry are common to all living organism How does biochemistry impact you? Medicine Agriculture Industrial . | BCH 400/600 – Introductory Biochemistry Instructor: David Shintani Office: 311C Fleischmann Ag. Lab: 308 Fleischmann Ag. E-mail: shintani@unr.edu Phone: (775) 784-4631 Before BCH 400 After BCH 400 BCH 400 is heavy on content!!! Come to class!!!!!! Try not to fall behind!! Review lecture notes. http://www.ag.unr.edu/shintani/bch400-600/index.html Read book chapters. Principles of Biochemistry 4th Edition Principles of Biochemistry 3rd Edition Use tools to memorize Histidine? Study in groups Participate in the clicker system!!! 20 extra credit points!! Feel Free to see me! My office hours are Tuedays from 2:00 to 3:00 PM Or e-mail me for a private audience What is Biochemistry? Biochemistry = chemistry of life. Biochemists use physical and chemical principles to explain biology at the molecular level. Basic principles of biochemistry are common to all living organism How does biochemistry impact you? Medicine Agriculture Industrial applications Environmental applications Principle Areas of Biochemistry Structure and function of biological macromolecules Metabolism – anabolic and catabolic processes. Molecular Genetics – How life is replicated. Regulation of protein synthesis Life Before Biochemistry Once upon a time, a long long time ago Vitalism: idea that substances and processes associated with living organisms did not behave according to the known laws of physics and chemistry Evidence: Only living things have a high degree of complexity Only living things extract, transform and utilize energy from their environment Only living things are capable of self assembly and self replication Origins of Biochemistry: A challenge to “Vitalism.” Famous Dead Biochemist! Fallacy #1: Biochemicals can only be produced by living organisms 1828 Friedrich Wohler Dead Biochemist #1 Fallacy #2: Complex bioconversion of chemical substances require living matter 1897 Eduard Buchner Dead Biochemists #2 Glucose + Dead Yeast = Alcohol .