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NEURAL STEM CELLS NEW PERSPECTIVES

Twenty years after the discovery of neural stem cells, the question whether the central nervous system can be considered among regenerative tissues is still open. On one side, deep characterization of neural stem and progenitor cells, their niches, and their progeny in brain neurogenic sites overtly showed that new neurons can be generated in the brain of adult mammals, including humans. On the other side, many problems arise when stem cells encounter the mature brain parenchyma, still hampering the development of efficacious therapeutic approaches with endogenous or exogenously-delivered neural stem cells. This book tries to make the point on these. | NEURAL STEM CELLS -NEW PERSPECTIVES Edited by Luca Bonfanti Neural Stem Cells - New Perspectives http dx.doi.org 10.5772 56573 Edited by Luca Bonfanti Contributors Kaneyasu Nishimura Luca Colucci-D Amato MariaTeresa Gentile Luca Bonfanti Emilia Madarász Caetana Carvalho Bruno P Carreira Ines Araujo Ana Isabel Santos Angelique Bordey Manavendra Pathania Shan Bian Emmanuel Moyse Young Gyu Chai Nando Dulal Das Verdon Taylor Stefano Pluchino Matteo Donega Elena Giusto Chiara Cossetti Teri Belecky-Adams Luciano Conti Simona Casarosa Jacopo Zasso Joshua Goldberg Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2013 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. However users who aim to disseminate and distribute copies of this book as a whole must not seek monetary compensation for such service excluded InTech representatives and agreed collaborations . After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Iva Lipovic Technical Editor InTech DTP team Cover InTech Design team First .