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A REPORT COMMISSIONED BY THE CENTERS FOR DISEASE CONTROL AND PREVENTION

Tham khảo sách 'a report commissioned by the centers for disease control and prevention', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | UNIVERSITY OF WASHINGTON CENTER FOR GENOMICS AND PUBLIC HEALTH ASTHMA GENOMICS IMPLICATIONS FOR PUBLIC HEALTH A REPORT COMMISSIONED BY THE CENTERS FOR DISEASE CONTROL AND PREVENTION ASTHMA GENOMICS A REPORT ON THE IMPLICATIONS FOR PUBLIC HEALTH TABLE OF CONTENTS Executive Summary.i Purpose of report.1 Asthma as a Public Health Concern.1 Genomics and Public Health.2 METHODS Defining the Question.3 Source of Experts for Consultation.4 Process for Expert Consultation.4 Process for Community Consultation.4 FINDINGS The Short-term View The Importance of Pharmacogenomics.5 The Long-term View Other Applications of Genomics to Public health.7 The Importance of Genomics Research for the Public Health Agenda.8 Promoting Dialogue and Consensus.13 Implications for public HEALTH REVISITING OTHER Perspectives.15 Implications for Public Health Action.16 Research.16 Clinical Practice Guidelines.17 Creating an efficient infrastructure.17 References.19 Appendices Appendix A List of Asthma Working Group Members Timeline.25 Appendix B Acknowledgements.26 Appendix C Consultation Guide.28 March 2004 EXECUTIVE SUMMARY With support from the Centers for Disease Control and Prevention CDC the University of Washington Center for Genomics and Public Health convened an Asthma Working Group to evaluate the implications of genomics for public health efforts related to asthma. Between January and October of 2003 the Working Group gathered information from the medical literature held discussions among working group members and consulted with a diverse group of experts to address this question. A preliminary report of the Group s findings was presented at a meeting held in Seattle WA on September 22nd and 23rd 2003. This report summarizes these findings incorporating discussions at the Sept 22-23 meeting. Asthma is a chronic lung condition characterized by airway inflammation hyperreactivity and reversible airway obstruction. The disease is found disproportionately among children and minorities and