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Progestogen-only Implants

Recent reviews have addressed issues of cigarette smoke exposure and various facets of reproduction including delayed time to conception, ovarian effects and premature menopause, implantation failure, fetal growth restriction and growth retardation, placental abnormalities, reduced fecundity, congenital abnormalities, and effects on male reproduction [32-34]. However, most prior reviews have not considered smoke's interaction with the oviduct, an organ vital to reproduction. The purpose of this paper is to review the functions of the oviduct, in particular those that involve movement of gametes and embryos, and to evaluate evidence that exposure to mainstream or side- stream cigarette smoke can negatively impact oviductal functioning and thereby adversely affect reproductive out- comes. We will also consider evidence. | -------FACULTY-------- -----OF SEXUAL------ REPRODUCTIVE HEALTHCARE Faculty of Sexual Reproductive Healthcare Clinical Guidance Progestogen-only Implants Clinical Effectiveness Unit April 2008 Updated January 2009 ISSN 1755-103X DETAILS OF CHANGES TO ORIGINAL GUIDANCE DOCUMENT In September 2008 Schering-Plough themanufacturer of the progestogen-only implant Implanon updated the Summary of Product Characteristics SPC and issued revised insertion site guidance details of which are included in this website version of the Clinical Effectiveness Unit CEU Guidance Document p. 6 . The print version of this CEU Guidance Document issued in April 2008 contained some inconsistencies that the CEU has corrected in this version. These corrections are to Table 2 p. 6 the Summary Points p. 11 and to Question 10 p. 13 pertaining to the use of progestogen-only implants following abortion. Published by the Faculty of Sexual and Reproductive Healthcare Registered in England No. 2804213 and Registered Charity No. 1019969 First published in April 2008 Updated January 2009 Copyright Faculty of Sexual and Reproductive Healthcare 2008 Permission granted to reproduce for personal and educational use only. Commercial copying hiring and lending are prohibited. --------FACULTY-------- ------OF SEXUAL------ REPRODUCTIVE ----HEALTHCARE---- Faculty of Sexual and Reproductive Healthcare Clinical Effectiveness Unit A unit funded by the FSRH and supported by the University of Aberdeen to provide guidance on evidence-based practice FSRH Guidance April 2008 Progestogen-only Implants Date of planned revision 2013 Purpose and scope This Guidance provides evidence-based recommendations and good practice points for clinicians on the use of progestogen-only implants. Currently the only progestogen implant licensed for use as contraception in the UK is the etonogestrel ENG implant Implanon .1 This Guidance focuses on the evidence directly relating to the ENG implant from hereon referred to as the .