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Báo cáo y học: "Nef gene evolution from a single transmitted strain in acute SIV infection"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Retrovirology Research cung cấp cho các bạn kiến thức về ngành y đề tài:"Nef gene evolution from a single transmitted strain in acute SIV infection. | Retrovirology BioMed Central Research Nef gene evolution from a single transmitted strain in acute SIV infection Benjamin N Bimber1 Pauline Chugh2 Elena E Giorgi3 4 Baek Kim2 Anthony L Almudevar5 Stephen Dewhurst2 David H O Connor1 and Ha Youn Lee 5 Open Access Address Wisconsin National Primate Research Center and Department of Pathology and Laboratory Medicine University of Wisconsin-Madison Madison Wisconsin 53706 USA - Departments of Microbiology and Immunology University of Rochester Medical Center Rochester New York 14642 USA 3Theoretical Biology and Biophysics Los Alamos National Laboratory Los Alamos New Mexico 87545 USA 4Mathematics and Statistics University of Massachusetts Amherst Massachusetts 01002 USA and 5Biostatistics and Computational Biology University of Rochester Medical Center Rochester New York 14642 USA Email Benjamin N Bimber - bimber@wisc.edu Pauline Chugh - Pauline_Chugh@urmc.rochester.edu Elena E Giorgi - egiorgi@lanl.gov Baek Kim - baek_kim@urmc.rochester.edu Anthony L Almudevar - Anthony_Almudevar@urmc.rochester.edu Stephen Dewhurst-Stephen_Dewhurst@urmc.rochester.edu David H O Connor - doconnor@primate.wisc.edu Ha Youn Lee - hayoun@bst.rochester.edu Corresponding author Published 8 June 2009 Received 29 January 2009 Retrovirology 2009 6 57 doi 10.1186 1742-4690-6-57 Accepted 8 June 2009 This article is available from http www.retrovirology.cOm content 6 1 57 2009 Bimber et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The acute phase of immunodeficiency virus infection plays a crucial role in determining steady-state virus load and subsequent progression of disease in both humans and nonhuman primates. The acute period is also the time when vaccine-mediated effects on .