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Báo cáo khoa học: "Reduction of D-dimer levels after therapeutic administration of antithrombin in acquired antithrombin deficiency of severe sepsis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Reduction of D-dimer levels after therapeutic administration of antithrombin in acquired antithrombin deficiency of severe sepsis. | Available online http ccforum.eom content 9 6 R596 Open Access Research Reduction of D-dimer levels after therapeutic administration of antithrombin in acquired antithrombin deficiency of severe sepsis Jordan Kountchev1 Klaudija Bijuklic2 Romuald Bellmann3 Christian J Wiedermann4 and Michael Joannidis5 Resident Medical Intensive Care Unit Division of General Internal Medicine Department of Internal Medicine Medical University Innsbruck Austria 2Resident Laboratory for Inflammation Research Division of General Internal Medicine Department of Internal Medicine Medical University Innsbruck Austria 3Associate Professor Medical Intensive Care Unit Division of General Internal Medicine Department of Internal Medicine Medical University Innsbruck Austria 4Professor Division Head 2nd Division of Internal Medicine Department of Medicine Central Hospital of Bolzano Bozen Italy 5Associate Professor Director of the Medical Intensive Care Unit Division of General Internal Medicine Department of Internal Medicine Medical University Innsbruck Austria Corresponding author Michael Joannidis michael.joannidis@uibk.ac.at Received 7 May 2005 Revisions requested 23 Jun 2005 Revisions received 14 Aug 2005 Accepted 24 Aug 2005 Published 19 Sep 2005 Critical Care 2005 9 R596-R600 DOI 10.11 86 cc3808 This article is online at http ccforum.com content 9 6 R596 2005 Kountchev et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction In acute disseminated intravascular coagulation the effect of antithrombin AT administration on elevated levels of D-dimer is not well established. In the present study we report on changes in circulating levels of D-dimer in response to administration of AT in a series of patients with acquired AT .