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Báo cáo khoa hoc:" Physico-chemical characterization of nanoemulsions in cosmetic matrix enriched on omega-3"

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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Physico-chemical characterization of nanoemulsions in cosmetic matrix enriched on omega-3 | Kabri et al. Journal of Nanobiotechnology 2011 9 41 http www.jnanobiotechnology.eom content 9 1 41 JOURNAL OF NANOBIOTECHNOLOGY RESEARCH Open Access Physico-chemical characterization of nanoemulsions in cosmetic matrix enriched on omega-3 Tin-hinan Kabri Elmira Arab-Tehrany Nabila Belhaj and Michel Linder Abstract Background Nano-emulsions as non-equilibrium systems present characteristics and properties which depend not only on composition but also on their method of preparation. To obtain better penetration nanocosmeceuticals use nano-sized systems for the delivery of active ingredients to targeted cells. In this work nano-emulsions composed of miglyol rapeseed oil and salmon oil were developed as a cosmetic matrix. Measurements of different physico-chemical properties of nano-emulsions were taken according to size electrophoretic mobility conductivity viscosity turbidity cristallization and melting point. The RHLB was calculated for each formulation in order to achieve maximum stability. Results Both tween 80 and soya lecithin were found to stabilize formulations. The results showed that rapeseed oil and miglyol are the predominant parameters for determining the expression of results concerning the characterization of emulsion. Based on the mixture design we achieved the optimal point using the following formulation 56.5 rapessed oil 35.5 miglyol and 8 salmon oil. We considered this formulation to be the best as a nanocosmeceutical product due to the small size good turbidity and average HLB. Conclusions This study demonstrates the influence of formulation on the physico-chemical properties of each nano-emulsion obtained by the mixture design. Introduction Cosmetics represent an important industry worldwide especially in Europe. The matrix of cosmetics is not simple it usually contains a high number of ingredients and often requires time-consuming and tedious sample treatments 1 2 . Nanotechnology is a key technology leading to product innovation. Nano-emulsions

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