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Báo cáo khoa học " An examination of antibacterial and antifungal properties of constituents of Shiitake (Lentinula edodes) and Oyster (Pleurotus ostreatus) mushrooms "

Antibiotic agents have been in widespread and largely effective therapeutic use since their discovery in the 20th century. However, the emergence of multi-drug resistant pathogens now presents an increasing global challenge to both human and veterinary medicine. It is now widely acknowledged that there is a need to develop novel antimicrobial agents to minimize the threat of further antimicrobial resistance. With this in mind, a study was undertaken to examine the antimicrobial properties of aqueous extracts of ‘exotic’ Shiitake and Oyster mushrooms on a range of environmental and clinically important microorganisms. Method: Several batches of Shiitake and oyster mushrooms were purchased fresh from a local supermarket and underwent. | Complementary Therapies in Clinical Practice 15 2009 5-7 Contents lists available at ScienceDirect Complementary Therapies in Clinical Practice journal homepage www.elsevier.com locate ctnm An examination of antibacterial and antifungal properties of constituents of Shiitake Lentinula edodes and Oyster Pleurotus ostreatus mushrooms Rachel Hearsta b David Nelson a Graham McCollum a B. Cherie Millar c Yasunori Maeda c d Colin E. Goldsmith c Paul J. Rooneyc Anne Loughreyc J.R. Raoa John E. Moore c d a Applied Plant Science Division Agri-Food Biosciences Institute Newforge Lane Belfast BT9 5PX Northern Ireland UK b Grosvenor Grammar School Cameronian Drive Belfast BT5 6AX Northern Ireland UK c Northern Ireland Public Health Laboratory Department of Bacteriology Belfast City Hospital Lisburn Road Belfast BT9 7AD Northern Ireland UK d School of Biomedical Sciences Centre for Molecular Biosciences University of Ulster Cromore Road Coleraine Co. Londonderry BT52 1SA Northern Ireland UK ABSTRACT Keywords Antibiotic resistance Herbal remedy Shiitake mushroom Pseudomonas aeruginosa Cystic fibrosis Background Antibiotic agents have been in widespread and largely effective therapeutic use since their discovery in the 20th century. However the emergence of multi-drug resistant pathogens now presents an increasing global challenge to both human and veterinary medicine. It is now widely acknowledged that there is a need to develop novel antimicrobial agents to minimize the threat of further antimicrobial resistance. With this in mind a study was undertaken to examine the antimicrobial properties of aqueous extracts of exotic Shiitake and Oyster mushrooms on a range of environmental and clinically important microorganisms. Method Several batches of Shiitake and oyster mushrooms were purchased fresh from a local supermarket and underwent aqueous extraction of potential antimicrobial components. After reconstitution aqueous extracts were tested qualitatively against a panel of 29 .