Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo y học: "Acute myopathy secondary to oral steroid therapy in a 49-year-old man: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Acute myopathy secondary to oral steroid therapy in a 49-year-old man: a case report. | Khan and Larson Journal of Medical Case Reports 2011 5 82 http www.jmedicalcasereports.eom content 5 1 82 JOURNALOF medical case reports CASE REPORT Open Access Acute myopathy secondary to oral steroid therapy in a 49-year-old man a case report Muhammad A Khan Eric Larson Abstract Introduction Acute myopathy caused by oral corticosteroids is rare. We present a case of myopathy occurring after two doses of methylprednisolone. Typically acute steroid myopathy occurs with therapy using intravenous corticosteroids at high doses. Acute myopathy developing very early in the course of treatment with oral corticosteroids has been reported only once in the literature. Corticosteroid therapy may be complicated by myopathy usually chronic after prolonged high-dose therapy. Acute myopathy caused by exogenous corticosteroids is rare usually with intravenous corticosteroids at high doses. Case presentation A 49-year-old Caucasian man developed acute myopathy after taking oral methylprednisolone for only two days 24 mg on day 1 and 20 mg on day 2. He discontinued the medication because of new-onset myalgias and lethargy on day 3 and was seen in our clinic four days after beginning therapy. He completely recovered in four weeks by discontinuing the corticosteroids. Conclusion Among the many complications of corticosteroid therapy acute myopathy is very rare. It requires prompt recognition and adjustment of therapy. Introduction In 1932 Cushing 1 described myopathy as a clinical feature of hypercortisolism. Corticosteroids were introduced into clinical practice in 1948 and in 1958 Dubois 2 reported the first patient with myopathy resulting from iatrogenic corticosteroids. Since corticosteroid therapy s introduction into clinical practice both acute and chronic steroid myopathies have been well recognized. Chronic steroid myopathy is more common and develops after prolonged usage of steroids 3 4 . Acute steroid myopathy ASM is less common and develops early in the course of .