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báo cáo khoa học: " Manifestation of a sellar hemangioblastoma due to pituitary apoplexy: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Manifestation of a sellar hemangioblastoma due to pituitary apoplexy: a case report | Schăr et al. Journal of Medical Case Reports 2011 5 496 http www.jmedicalcasereports.eom content 5 1 496 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Manifestation of a sellar hemangioblastoma due to pituitary apoplexy a case report 1 2 3 1 Ralph T Schar Istvan Vajtai Rahel Sahli and Rolf W Seiler Abstract Introduction Hemangioblastomas are rare benign tumors occurring in any part of the nervous system. Most are found as sporadic tumors in the cerebellum or spinal cord. However these neoplasms are also associated with von Hippel-Lindau disease. We report a rare case of a sporadic sellar hemangioblastoma that became symptomatic due to pituitary apoplexy. Case presentation An 80-year-old otherwise healthy Caucasian woman presented to our facility with severe headache attacks hypocortisolism and blurred vision. A magnetic resonance imaging scan showed an acute hemorrhage of a known stable and asymptomatic sellar mass lesion with chiasmatic compression accounting for our patient s acute visual impairment. The tumor was resected by a transnasal transsphenoidal approach and histological examination revealed a capillary hemangioblastoma World Health Organization grade I . Our patient recovered well and substitutional therapy was started for panhypopituitarism. A follow-up magnetic resonance imaging scan performed 16 months postoperatively showed good chiasmatic decompression with no tumor recurrence. Conclusions A review of the literature confirmed supratentorial locations of hemangioblastomas to be very unusual especially within the sellar region. However intrasellar hemangioblastoma must be considered in the differential diagnosis of pituitary apoplexy. Introduction Hemangioblastomas HBLs are benign slowly growing and highly vascular tumors of the central nervous system CNS accounting for just 1 to 2.5 of all intracranial neoplasms and 7 to 12 of primary tumors located in the posterior fossa 1 . In up to one in four cases of HBL there is an association with .