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Báo cáo khoa học: " Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition"

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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition. | Radiation Oncology BioMed Central Open Access Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition Kjersti Flatmark1 2 Ragnhild V Nome1 Sigurd Folkvord1 Ảse Bratland1 3 Heidi Rasmussen1 Mali Strand Ellefsen4 0ystein Fodstad1 and Anne Hansen Ree 1 3 Address Department of Tumor Biology Rikshospitalet-Radiumhospitalet Medical Center University of Oslo 0310 Oslo Norway 2Department of Surgical Oncology Rikshospitalet-Radiumhospitalet Medical Center 0310 Oslo Norway 3Department of Medical Oncology and Radiotherapy Rikshospitalet-Radiumhospitalet Medical Center 0310 Oslo Norway and 4Department of Radiation Biology Rikshospitalet-Radiumhospitalet Medical Center 0310 Oslo Norway Email Kjersti Flatmark - kjersti.flatmark@labmed.uio.no Ragnhild V Nome - r.v.nome@studmed.uio.no Sigurd Folkvord - sigurf@medisin.uio.no Ảse Bratland - ase.bratland@medisin.uio.no Heidi Rasmussen - heidi.rasmussen@labmed.uio.no Mali Strand Ellefsen - mali.strand@labmed.uio.no 0ystein Fodstad - oystein.fodstad@medisin.uio.no Anne Hansen Ree - a.h.ree@medisin.uio.no Corresponding author Published 03 August 2006 Radiation Oncology 2006 1 25 doi 10.1186 1748-717X-1-25 Received 20 June 2006 Accepted 03 August 2006 This article is available from http www.ro-journal.eom content 1 1 25 2006 Flatmark et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The tumor response to preoperative radiotherapy of locally advanced rectal cancer varies greatly warranting the use of experimental models to assay the efficacy of molecular targeting agents in rectal cancer radiosensitization. Histone deacetylase HDAC inhibitors agents that .