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Báo cáo khoa học: " Prediction of clinical toxicity in localized cervical carcinoma by radio-induced apoptosis study in peripheral blood lymphocytes (PBLs)"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Prediction of clinical toxicity in localized cervical carcinoma by radio-induced apoptosis study in peripheral blood lymphocytes (PBLs). | Radiation Oncology BioMed Central Research Open Access Prediction of clinical toxicity in localized cervical carcinoma by radio-induced apoptosis study in peripheral blood lymphocytes PBLs Elisa Bordón1 Luis Alberto Henriquez Hernandez 1 2 Pedro C Lara1 3 Beatriz Pinar1 3 Fausto Fontes1 Carlos Rodríguez Gallego1 4 and Marta Lloret1 3 Address 1Canary Institute for Cancer Research ICIC Las Palmas Spain 2Clinic Sciences Department of Las Palmas de Gran Canaria University ULPGC Las Palmas Spain 3Radiation Oncology Department Hospital Universitario de Gran Canaria Dr. Negrin Las Palmas Spain and 4Inmunology Department Hospital Universitario de Gran Canaria Dr. Negrin Las Palmas Spain Email Elisa Bordón - elisarbr@gmail.com Luis Alberto Henriquez Hernandez - lhenriquez@dcc.ulpgc.es Pedro C Lara - plara@dcc.ulpgc.es Beatriz Pinar - beapinsed@hotmail.com Fausto Fontes - faustofontes@gmail.com Carlos Rodríguez Gallego - jrodgal@gobiernodecanarias.org Marta Lloret - mllosae@hotmail.com Corresponding author Published 26 November 2009 Received 20 August 2009 Accepted 26 November 2009 Radiation Oncology 2009 4 58 doi 10.1186 1748-717X-4-58 This article is available from http www.ro-journal.com content 4 1 58 2009 Bordón et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Cervical cancer is treated mainly by surgery and radiotherapy. Toxicity due to radiation is a limiting factor for treatment success. Determination of lymphocyte radiosensitivity by radio-induced apoptosis arises as a possible method for predictive test development. The aim of this study was to analyze radio-induced apoptosis of peripheral blood lymphocytes. Methods Ninety four consecutive patients suffering from cervical carcinoma diagnosed and .