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Báo cáo y học: "Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia. | Sugawara et al. Annals of General Psychiatry 2011 10 21 http www.annals-general-psychiatry.eom content 10 1 21 ANNALS OF GENERAL PSYCHIATRY PRIMARY RESEARCH Open Access Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia 1.2 2 1.2 3.4 56 2 Norio Sugawara 1 Norio Yasui-Furukori Yasushi Sato 1 Ikuko Kishida Hakuei Yamashita Manabu Saito Hanako Furukori7 Taku Nakagami2 8 Mitsunori Hatakeyama9 and Sunao Kaneko2 Abstract Background Lifestyle factors such as an unbalanced diet and lack of physical activity may affect the prevalence of metabolic syndrome MetS in schizophrenic patients. The aim of this study was to compare the MetS prevalence between inpatients and outpatients among schizophrenic population in Japan. Methods We recruited inpatients n 759 and outpatients n 427 with a Diagnostic and Statistical Manual of Mental Disorders fourth edition DSM-IV diagnosis of schizophrenia or schizoaffective disorder from 7 psychiatric hospitals using a cross-sectional design. MetS prevalence was assessed using three different definitions including the adapted National Cholesterol Education Program Adult Treatment Panel ATP III-A . Results The overall MetS prevalences based on the ATP III-A definition were 15.8 in inpatients and 48.1 in outpatients. In a logistic regression model with age and body mass index as covariates being a schizophrenic outpatient compared to being a schizophrenic inpatient was a significant independent factor odds ratio 3.66 for males 2.48 for females in the development of MetS under the ATP III-A definition. The difference in MetS prevalence between inpatients and outpatients was observed for all age groups in males and for females over 40 years of age. Conclusions Outpatients with schizophrenia or schizoaffective disorder in Japan had a high prevalence of MetS compared to inpatients. MetS in schizophrenic outpatients should be carefully monitored to minimize the risks. A change of .