Đang chuẩn bị liên kết để tải về tài liệu:
báo cáo hóa học: " Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease | Journal of Neuroinflammation BioMed Central Short report Open Access Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer s disease Jeroen JM Hoozemans 1 5 Elise S van Haastert1 Robert Veerhuis3 4 Thomas Arendt4 Wiep Scheper2 Piet Eikelenboom3 and Annemieke JM Rozemuller1 Address Department of Neuropathology Academic Medical Center P.O. Box 22700 1100 DE Amsterdam The Netherlands 2Neurogenetics Laboratory Academic Medical Center University of Amsterdam Amsterdam The Netherlands 3Department of Psychiatry VU University medical center Amsterdam The Netherlands 4Department of Clinical Chemistry and Alzheimer Center VU University medical center Amsterdam The Netherlands and 5Department of Neuroanatomy Paul Flechsig Institute for Brain Research University of Leipzig Leipzig Germany Email Jeroen JM Hoozemans - j.j.hoozemans@amc.uva.nl Elise S van Haastert - e.s.vanhaaster@amc.uva.nl Robert Veerhuis - r.veerhuis@vumc.nl Thomas Arendt - Thomas.Arendt@medizin.uni-leipzig.de Wiep Scheper - w.scheper@amc.uva.nl Piet Eikelenboom - piete@ggzba.nl Annemieke JM Rozemuller - j.m.rozemuller@amc.uva.nl Corresponding author Published 21 November 2005 Received 24 October 2005 __ AA1- . A I IO I7A AAoa 1 1-7 Accepted 21 November 2005 Journal of Neuroinflammation 2005 2 27 doi l0.ll86 1742-2094-2-27 This article is available from http www.jneuroinflammation.com content 2 1 27 2005 Hoozemans et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Neuronal expression of cyclooxygenase-2 COX-2 and cell cycle proteins is suggested to contribute to neurodegeneration during Alzheimer s disease AD . The stimulus that induces .