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Work Programme 2011 - COOPERATION THEME 1 Health

Research should focus on the development and production of new high-affinity, non-immunoglobulin protein scaffolds as an alternative to antibodies or oligonucleotides. Projects should aim at developing new, efficient and safe therapies by combining high specificity with stable production characteristics. Projects should include preclinical studies, methods for scale-up and GMP as appropriate, should combine academic, clinical and industrial expertise and implement a translational approach towards clinical trials (clinical proof-of-concept and/or phase I/II clinical studies). A strong level of SME participation is required. Note: Limits on the EU financial contribution apply. These are implemented strictly as formal eligibility criteria. . | Work Programme 2011 Cooperation THEME 1 Health European Commission C 2010 4900 of 19 July 2010 FP7 Cooperation Work Programme Health-2011 Page 2 of 74 FP7 Cooperation Work Programme Health-2011 I CONTEXT.4 II CONTENT OF CALLS.10 1. Biotechnology generic tools and medical technologies for human health.10 1.1 High-throughput research.10 1.2 Detection diagnosis and monitoring.12 1.3 Suitability safety efficacy of therapies.12 1.4 Innovative therapeutic approaches and interventions.12 2. TRANSLATING RESEARCH FOR HUMAN HEALTH. 17 2.1 Integrating biological data and processes large-scale data gathering systems biology.18 2.1.1 Large-scale data gathering.18 2.1.2 SYSTEMS BIOLOGY.22 2.2 Research on the brain and related diseases human development and ageing.22 2.2.1 Brain and brain-related diseases.22 2.2.2 Human development and ageing.25 2.3 Translational research in major infectious diseases to confront major threats to public health.27 2.3.1 Anti-microbial drug resistance.27 2.3.2 HIV AIDS malaria and tuberculosis.30 2.3.3 Potentially new and re-emerging epidemics.30 2.3.4 Neglected infectious diseases.32 2.4 Translational research in other major diseases.32 2.4.1 Cancer.32 2.4.2 Cardiovascular diseases.34 2.4.3 Diabetes and obesity.36 2.4.4 Rare diseases.39 2.4.5 Other chronic diseases.39 3. OPTIMISING THE DELIVERY OF HEALTHCARE TO European citizens.40 3.1 Translating the results of clinical research outcome into clinical practice including better use of medecines and appropriate use of behavioural and organisational interventions and new health therapies and technologies.40 3.2 Quality efficiency and solidarity of healthcare systems including transitional health systems.40 3.3 Health promotion.40 3.4 International public health health systems.43 4. OTHER ACTIONS ACROSS THE HEALTH THEME.45 4.1 Coordination and support actions across the theme.45 4.2 Responding to EUpolicy needs.47 III IMPLEMENTATION.51 Call title HEALTH 2011 single-stage.51 Call title HEALTH 2011 .