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Báo cáo hóa học: " Markedly impaired bilateral coordination of gait in post-stroke patients: Is this deficit distinct from asymmetry? A cohort study"
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Markedly impaired bilateral coordination of gait in post-stroke patients: Is this deficit distinct from asymmetry? A cohort study | Meijer et al. Journal of NeuroEngineering and Rehabilitation 2011 8 23 http www.jneuroengrehab.eom content 8 1 23 Iril JOURNAL OF NEUROENGINEERING NCR AND REHABILITATION RESEARCH Open Access Markedly impaired bilateral coordination of gait in post-stroke patients Is this deficit distinct from asymmetry A cohort study 1.2.3 4.5 1 6 6 1 Ronald Meijer1 Meir Plotnik Esther Groot Zwaaftink Rob C van Lummel Erik Ainsworth Juan D Martina and Jeffrey M Hausdorff4 7 Abstract Background Multiple aspects of gait are typically impaired post-stroke. Asymmetric gait is common as a consequence of unilateral brain lesions. The relationship between the resulting asymmetric gait and impairments in the ability to properly coordinate the reciprocal stepping activation of the legs is not clear. The objective of this exploratory study is to quantify the effects of hemiparesis on two putatively independent aspects of the bilateral coordination of gait to gain insight into mechanisms and their relationship and to assess their potential as clinical markers. Methods Twelve ambulatory stroke patients and age-matched healthy adults wore a tri-axial piezo-resistive accelerometer and walked back and forth along a straight path in a hall at a comfortable walking speed during 2 minutes. Gait speed gait asymmetry GA and aspects of the bilateral coordination of gait BCG were determined. Bilateral coordination measures included the left-right stepping phase for each stride i consistency in the phase generation O_CV accuracy in the phase generation O_AB3 and Phase Coordination Index PCI a combination of accuracy and consistency of the phase generation. Results Group differences p 0.001 were observed for gait speed 1.1 0.1 versus 1.7 0.1 m sec for patients and controls respectively GA 26.3 5.6 versus 5.5 1.2 correspondingly and PCI 19.5 2.3 versus 6.2 1.0 correspondingly . A significant correlation between GA and PCI was seen in the stroke patients r 0.94 p 0.001 but not in the controls. Conclusions .