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Báo cáo hóa học: " Fractal dimension approach in postural control of subjects with Prader-Willi Syndrome"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Fractal dimension approach in postural control of subjects with Prader-Willi Syndrome | Cimolin et al. Journal of NeuroEngineering and Rehabilitation 2011 8 45 http www.jneuroengrehab.eom content 8 1 45 Iril JOURNAL OF NEUROENGINEERING NCR AND REHABILITATION RESEARCH Open Access Fractal dimension approach in postural control of subjects with Prader-Willi Syndrome 12 13 1 -4 2 1 Veronica Cimolin Manuela Galli Chiara Rigoldi Graziano Grugni Luca Vismara Luca Mainardi and Paolo Capodaglio2 Abstract Background Static posturography is user-friendly technique suitable for the study of the centre of pressure CoP trajectory. However the utility of static posturography in clinical practice is somehow limited and there is a need for reliable approaches to extract physiologically meaningful information from stabilograms. The aim of this study was to quantify the postural strategy of Prader-Willi patients with the fractal dimension technique in addition to the CoP trajectory analysis in time and frequency domain. Methods 11 adult patients affected by Prader-Willi Syndrome PWS and 20 age-matched individuals Control group CG were included in this study. Postural acquisitions were conducted by means of a force platform and the participants were required to stand barefoot on the platform with eyes open and heels at standardized distance and position for 30 seconds. Platform data were analysed in time and frequency domain. Fractal Dimension FD was also computed. Results The analysis of CoP vs. time showed that in PWS participants all the parameters were statistically different from CG with greater displacements along both the antero-posterior and medio-lateral direction and longer CoP tracks. As for frequency analysis our data showed no significant differences between PWS and CG. FD evidenced that PWS individuals were characterized by greater value in comparison with CG. Conclusions Our data showed that while the analysis in the frequency domain did not seem to explain the postural deficit in PWS the FD method appears to provide a more informative description of it .