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THERAPEUTIC GASTROINTESTINAL ENDOSCOPY

Therefore, the brain hormonal milieu in which exogenous hormones are introduced is markedly different in menopause from that in menstruating women. In the ovariectomized animals, however, the hormonal changes in the animals are abrupt in contrast to the gradual hormonal changes found in the menopausal transition. It might be the concerted lack of estradiol and progesterone that facilitate the seizure susceptibility. Both estradiol and progesterone affect γ-amino butyric acid (GABA) ergic function (Scharfman et al, 2005; Nakumura et al, 2005; Kokate et al, 1994). The simultaneous decrease of estrogen and progesterone may thereby lead to a decrease in GABAergic inhibition, facilitating seizures. Recently published results by Lavaque et. | THERAPEUTIC GASTROINTESTINAL ENDOSCOPY Edited by Oliviu Pascu and Marcel Tantau INTECHWEB.ORG Therapeutic Gastrointestinal Endoscopy Edited by Oliviu Pascu and Marcel Tantau Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access articles distributed under the Creative Commons Non Commercial Share Alike Attribution 3.0 license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published articles. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Masa Vidovic Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright Sebastian Kaulitzki 2011. Used under license from Shutterstock.com First published September 2011 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Therapeutic Gastrointestinal Endoscopy Edited by Oliviu Pascu and Marcel Tantau p. cm. ISBN 978-953-307-743-7 ikrrr iJ OPEN ACCESS INI Cvn PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .