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Sửa chữa các khuyết tật xương

Phương pháp tiếp cận nhiều người sử dụng để sửa chữa các khuyết tật xương trong phẫu thuật chỉnh hình tái tạo, và ghép xương IS Tham gia vào thủ tục Hầu Mỗi. Các loại ghép xương phụ thuộc vào kết quả cuối cùng sử dụng và lâm sàng các kịch bản dự kiến . Tự sinh cancellous xương ghép, | The Biology of Bone Grafting Safdar N. Khan MD Frank P. Cammisa Jr MD HarvinderS. Sandhu MD Ashish D. Diwan MD PhD Federico P. Girardi MD and Joseph M. Lane MD Abstract Many approaches are used to repair skeletal defects in reconstructive orthopaedic surgery and bone grafting is involved in virtually every procedure. The type of bone graft used depends on the clinical scenario and the anticipated final outcome. Autogenous cancellous bone graft with its osteogenic osteoinductive and osteocon-ductive properties remains the standard for grafting. However the high incidence of morbidity during autogenous graft harvest may make the acquisition of grafts from other sources desirable. The clinical applications for each type of bone graft are dictated by the structure and biochemical properties of the graft. An elegant cellular and molecular cascade follows bone transplantation. Bone graft incorporation within the host whether autogenous or allogeneic depends on many factors type of graft autogenous versus allogeneic vascular versus nonvascular site of transplant quality of transplanted bone and host bone host bed preparation preservation techniques systemic and local disease and mechanical properties of the graft. J Am Acad Orthop Surg 2005 13 77-86 Functions of Bone Grafts Bone grafts serve a combined mechanical and biologic function depending on the desired clinical outcome one function may be more important than the other. For instance massive osteochondral grafts in limb salvage procedures for tumors serve a predominantly mechanical support function whereas autogenous bone graft derived from the iliac crest for posterolateral spine fusions provides a biologic stimulus for The transplantation of animal tissues into humans has been attempted since the time of Hippocrates. Evidence suggests that the ancient Hindus and Egyptians also undertook transplantation experiments however the first documented xenograft is attributed to Dutch surgeon Job van Mee kren who in the .