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CLINICIAN’S POCKET DRUG REFERENCE 2008 - part 5

Fluticasone, miệng (Flovent, Flovent Rotadisk) Sử dụng: * hen suyễn mãn tính * Hành động: Dùng ngoài steroid Liều lượng: Người lớn & Teens. 2-4 nhát thầu. Peds 4-11 y. Phạt cảnh cáo 50 mcg thầu: [C, M] Contra: Tiểu Rx của Disp asthmaticus tình trạng: Rotadisk bột khô: 50, 100, 250 mcg / kích hoạt SE: HA, | 106 Fluticasone Oral Fluticasone Oral Flovent Flovent Rotadisk Uses Chronic asthma Action Topical steroid Dose Adults Adolescents. 2-4 puffs bid. Peds 4-11 y. 50 mcg bid Caution C M Contra Primary Rx of status asthmaticus Disp Rotadisk dry powder 50 100 250 mcg activation SE HA dysphonia oral candidiasis Notes Risk of thrush rinse mouth after counsel on use of device Fluticasone Propionate Salmeterol Xinafoate Advair Diskus Advair HFA 45 21 115 21 230 21 inhaled aerosol WARNING Increased risk of worsening wheezing or asthma-related death with long acting p-2 adrenergic agonists Uses Maint therapy for asthma Action Corticosteroid w LA bronchodilator p-2 agonist Dose Adults Peds 12 y. 1 inhal bid q 12 h titrate to lowest effective dose 4 inhal or 920 84 mcg day max Caution C M Contra Acute asthma attack conversion from PO steroids w phenothiazines Disp Diskus met-dose inhal powder fluticasone sal-meterol in mcg 100 50 250 500 500 50 HFA aerosol 45 21 115 21 230 21 mg SE Upper resp Infxn pharyngitis HA Notes Combo of Flovent Serevent do not wash mouthpiece do not exhale into device ADVAIR HFA for patients not controlled on other medications eg low-medium dose inhal steroids or whose disease severity warrants 2 maintenance therapies Fluvastatin Lescol Uses Atherosclerosis primary hypercholesterolemia heterozygous familial hypercholesterolemia hypertriglyceridemia Action HMG-CoA reductase inhibitor Dose 20-40 mg BID PO or XL 80 day ị w hepatic impair Caution X - Contra Active liver Dz T LFTs PRG breastfeeding Disp Caps 20 40 mg XL 80 mg SE HA dyspepsia N D abd pain Notes Dose no longer limited to HS J LFT s Fluvoxamine Luvox WARNING Closely monitor for worsening depression or emergence of suicidality particularly in ped pts Uses OCD Action SSRI Dose Initial 50-mg single qhs dose T to 300 mg d in doses ị in elderly hepatic impair titrate slowly doses 100 mg Caution C - Interactions MAOIs phenothiazines SSRIs serotonin agonists others Contra MAOI w in 14 days Disp Tabs 25