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Handbook of Biochemical Kinetics

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The biotic world is doubtlessly the best known example of what Nobelist Murray Gell-Mann has termed ‘‘complex adaptive systems’’—a name given to those systems possessing the innate capacity to learn and evolve by utilizing acquired information. Those familiar with living systems cannot but marvel at each cell’s ability to grow, to sense, to communicate, to cooperate, to move, to proliferate, to die and, even then, to yield opportunity to succeeding cells. If we dare speak of vitalism, especially as the new millennium is eager to dawn, we only do so to recognize that homeostatic mechanisms endow cells with such remarkable resilience that early investigators mistook homeostasis as a persuasive indication that life is. | I KtAI MtN il llu I I II -Handbook OF ARRHENIUS Í ỈOCATALYSI I I Biochemical M B Kinetics TRANSITION SI N-LIMITED F E LE CTROC ATA LY GEN-TAMM MEC M DIALYSIS EQUILIBRIUM ENZYMES IN MET EQUILIBRIUM ISOTOP FLUORESCENCE RECOVERY AFTER PHOTOBLEACHINC ELIS-MENTEN EQUATIOI PRINCIPLE ENZYME ENERGETICS FROMM S METHOD FOR DERIVING ENZYME RAT OT HILL EQUATION PLOT GUGGENHEIM METHOD HALDANE RELATION EFFECT HEMOGLOBIN OXYGENATION HESS LAW HETEROTROPIC EFFE I NITI A MOBILIZED ENZYMES INDEFINIT G HYDROGEN TUNNELING HYPERCYC py DđttiéPL _ Ljr MNER-SPHtke tLEciRON TkANbFtk INTERFACE ACTIVATION IN LIPOLYSIS INTERNA TRINSIcR rDonald Allison TOPE EFFECT IN LINE MECHANISM IOI CHANGE ISOTOPE SCRAMBLING ISOTOPICALLY SENSITIVE STEP KLOTZ PLOT LA V1ER ADDUCT TWOM LIGAND FIELD SPLITTING LOCK-AND-KEY MODEL OF ENZYM T LINEAR FREE ENERGY RELATIONSHIP LINKED FUNCTIONS MASS-ACTION RATIO METAL-NUCLEOTIDE COMPLEX METABOLITE COMPARTMENTATION DETERMININ N NORTHROP ISOTOPE EFFECT METHOD MICROTUBULE ASSEMBLY KINETICS NSPORT METAL ION EXCHANGE TIMES MICROENVIRONMENT MULTIPLE ATTACK UCLEOPHILIC SUBSTITUTION REACTION NONLINEAR INHIBITION RANDOM SCISSIOI VTE MECHANISMS MYOGLOBIN OXYGENATION NUCLEATION ONE DIMENSIONA ION PACEMAKER REACTION PARTIAL EXCHANGE REACTIONS R ENTITY QUANTUM MECHANICAL TUNNELING MULTISTAG ISTANT METHOD POSITIVE COOPERATIVITY SCATCHARD PLOT GENERAL PRECAUTIONS RAPID BUFFER EXCHANGE RATI rriONAI rnRRFI ATION TIMF TtlRRIDITY KOTOPIC INi IRREVERSIBLE INHIBITOR INITIAL RAT Handbook of Biochemical Kinetics This Page Intentionally Left .

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