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Pharmaceutical Substances Syntheses, Patents, Applications - Part 126

Pharmaceutical Substances Syntheses, Patents, Applications - Part 126. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Meprobamate M 1251 CH Se03 3 2 3 H3c OH or microbiologicolly with Bocillus sphaericus vor. fusiformis ATCC 7055 selenium dioxide tert-amyl alcohol 160-methylcortisone Meprednisone Referenced s US 3 164 618 Schering Corp. 5.1.1965 prior. 23.7.1957 8.5.1958 . Taub D. et al. J. Am. Chem. Soc. JACSAT 82 4012 1960 80 4435 1958 . Oliveto E.P. et al. J. Am. Chem. Soc. JACSAT 80 4428 1958 . starting material for a Slates H.L. Wandler N.L. J. Org. Chem. JOCEAH 22 498 1957 . US 2 671 794 Glidden 1954 prior. 1950 1949 . alternative syntheses from hecogenin Nathansohn G.B. et al. Experientia EXPEAM 17 448 1961 . from sitosterin US 4 041 055 Upjohn 9.8.1977 prior. 17.11.1975 . Trade Name s F Betalone Lepetit wfm Policort Lepetit -comb. USA Betapar Parke Davis wfm I Corti-Bi Sidus wfm wfm Betapred Schering wfm Meprobamate atc nosbcoi Use tranquilizer RN 57-53-4 MF C9HlgN2O4 MW 218.25 EINECS 200-337-5 LD5 1 230 mg kg M i.v. 750 mg kg M p.o. 350 mg kg R i.v. 794 mg kg R p.o. CN 2-methyl-2-propyl-l 3-propanediol dicarbamate HCHO 1. COCI2 2. NH3 CHO HoI3V OH ch3 F 1. phosgene 2-methyl- form- 2-methyl-2- voleroldehyde oldehyde propyl-1 3-proponediol Meprobomote 1252 M Meproscillarin Reference s US 2 724 720 Carter Products 1955 prior. 1953 . Ludwig B.J. Piech E.C. J. Am. Chem. Soc. JACSAT 73 5779 1951 . Formulation s f. c. tabl. 200 mg 400 mg Trade Name s D Meprobamat Saar Philopharm Visano Kade F Equanil Sanofi Winthrop Meprobamate Richard Richard Novalm LDM Sante generics and numerous combination preparations GB Equagesic Wyeth -comb. I Meprob Tariff. Nazionale Quanil Wyeth J Atraxin Daiichi Erina Sumitomo Harmonin Yoshitomi Mepron Choseido Mepron Kanto Xalogen Ono USA Equagesic Wyeth-Ayerst Equanil Wyeth-Ayerst Miltown Wallace Meproscillarin atc coiab Rambufaside Meproscillaridin Use cardiac g 00 RN 33396-37-1 MF C H Og MW 544.69 EINECS 251-493-6 LD50 2800 flg kg M i.v. 12.5 mg kg M p.o. 5800 pg kg R i.v. 79 mg kg R p.o. CN 3ß -3- 6-deoxy-4-O-methyl-a-L-mannopyranosyl oxy .