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Pharmaceutical Substances Syntheses, Patents, Applications - Part 64

Pharmaceutical Substances Syntheses, Patents, Applications - Part 64. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Dicloxacillin D 631 GB Daranide Merck Sharp Dohme wfm I Antidrasi SmithKline Beecham Fenamide Farmigea Glaumid SIFI J Daranide Merck-Banyu USA Daranide Merck Dicloxacillin ATC JO1CFO1 Use antibiotic RN 3116-76-5 MF C19H17C12N3O5S MW 470.33 EINECS 221-488-3 CN 2S- 2a 5a 6ß -6- 3- 2 6-dichlorophenyl -5-methyl-4-isoxazolyl carbonyl amino -3 3-dimethyl-7-oxo-4-thia-1 -azabicyclo 3.2.0 heptane-2-carboxylic acid monosodium salt monohydrate RN 13412-64-1 MF C19H16Cl2N3NaO5S H2O MW 510.33 LD50 875 mg kg M i.v. 4560 mg kg M p.o. 520 mg kg R i.v. 3579 mg kg R p.o. 3 g kg dog p.o. Cl CHO H2N-OH hydroxylamine Cl2 CHClj methyl ocetoacetote NaOCH3 2 6-dichloro- benzaldehyde NaOH ----- 3- 2 6-dich1oro-phenyl -5-methyl-jsoxozole-4-carboxylic ocid 6-aminopeni-cillanic acid Os J00H r i ch3 H ch3 h2n h Reference s US 3 239 507 Beecham 8.3.1966 GB-prior. 17.10.1962 . GB 978 299 Beecham appl. 17.10.1962 addition to GB 905 778 from 14.3.1961 . BE657 504 Bayer appl. 23.12.1964 D-prior. 24.12.1963 . Formulation s cps. 500 mg as sodium salt Trade Name s D Dichlor-Stapenor Bayer F Cefaplus Labif -comb. wfm Diclocil Bristol wfm I Diclo Firma 1 632 D Dicycloverine Diclocil Bristol wfm Diclocillin Aristochimica wfm Diclocillin Lagap wfm Diclocta Lusofarmaco -comb. wfm Dicloeta Lusofarmaco -comb. wfm Diclomax Pulitzer wfm Dicloxapen Magis wfm J Diflor Coli wfm Etadipen Ghimas -comb. wfm Novapen IBP wfm Versaclox Bristol -comb. USA wfm numerous combination preparations Clocil Bristre-Banyu Combipenix Toyo Jozo -comb. Diclex Meiji Staphcillin Banyu Dycill Beecham wfm Dynapen Bristol wfm Pathocil Wyeth wfm Veracillin Ayerst wfm Dicycloverine Dicyclomine ATC A03AA07 Use antispasmodic anticholinergic RN 77-19-0 MF C19H35NO2 MW 309.49 EINECS 201-009-4 CN 1 1 -bicyclohexyl -1 -carboxylic acid 2- diethylamino ethyl ester hydrochloride RN 67-92-5 MF C19H35NO2 HC1 MW 345.96 EINECS 200-671-1 LD50 31.5 mg kg M i.v. 625 mg kg M p.o. 1290 mg kg R p.o. benzyl cyanide 1 5-dibromo- pentane 1-cyano-1 .