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Pharmaceutical Substances Syntheses, Patents, Applications - Part 26

Pharmaceutical Substances Syntheses, Patents, Applications - Part 26. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Bisantrene B 251 Stadalax Stada Chemie Tempolax Hommel GB Tirgon Woelm I Vinco OTW Vinco-Abführperlen OTW -comb. numerous combination preparations F Contalax 3M Santé J Dulcolax Boehringer Ing. Pilules Dupuis Synthélabo -comb. Prépacol Guerbet -comb. Dulcolax Boehringer Ing. Alaxa Angelini Dulcolax Fher Fisiolax Manetti Roberts -comb. Normalene Montefarmaco Anan Ono Biomit Sampo -comb. Cathalin Hokuriku -comb. Ethanis Taisho -comb. Lax Kanto -comb. Satolax-10 Sato Telemin Soft Funai -comb. Vernas Nippon Zoki -comb. Vencoll Maruko -comb. USA Dulcolax Novartis Consumer Evac-Q-Kwik Savage Fleet Prep Kits Fleet Bisantrene CL-216942 ATC LOI Use intercalanting antineoplastic against adult acute non-lymphocytic leucemia RN 78186-34-2 MF C22H22N8 MW 398.47 LDS0 245 mg kg M route unreported CN 9 10-anthracenedicarboxaldehyde bis 4 5-dihydro-l 7-imidazol-2-ylhydrazone dihydrochloride RN 71439-68-4 MF C22H22N8 2HC1 MW 471.40 anthracene vinylene carbonate KOH C2H5OH 9 10 11 12-tetrahydro-9 10- 4 5 l 3 díoxolo-anthracen-14-ane Pb OCOCH3 4. leod tetracetate. CHO 9 10-dihydro-9 10- 9 1O-anthracene- ethanoanthracene- dicarboxaldehyde nan H H 2-hydrazino- A2-imidazoline 11 12-diol I Reference s DOS 2 850 822 American Cyanamid appl. 23.11.1978 USA-prior. 28.11.1977 5.5.1978 19.9.1978 2.10.1978 . US4 187 373 AmericanCyanamid 5.2.1980 appl. 2.10.1978 . Murdock K.L. et al. J. Med. Chem. JMCMAR 25 505 1982 . Formulation s vial 50 mg 250 mg 500 mg Trade Name s F Zantrene Lederle 1990 as USA Cyabin Lederle as dihydrochloride wfm dihydrochloride wfm 252 B Bisbentiamine Bisbentiamine Benzoylthiamine disulfide ATC All Use neurotropic analgesic vitamin B -derivative RN 2667-89-2 MF C38H42NgO6S2 MW 770.94 EINECS 220-206-6 LD50 194 mg kg M i.v. 9 g kg M p.o. CN V A - dithiobis 2- 2- benzoyloxy cthyl -l-methyl-2 l-ethcnediyl -bis V- 4-amino-2-methyl-5-pyrimidinyl methyl fbrmamide cr t KI or K3 Fe CN 6 --------------------- I thiamine q. v. N- 4-omino-2-methylpyrimidin-5-ylmethyl -N- 4-hydroxy-1