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The effects of KEM CON ONG and KEM TRI BONG creams on doxorubicin induced skin ulcer in rats
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The present study evaluated the effects of topical administration of KEM CON ONG and KEM TRI BONG creams on doxorubicin-induced skin ulcer, and their systemic toxicity in ulcerated rats. The skin lesions were induced by a single intradermal injection of 0.2ml doxorubicin 1 mg/0.5ml on the dorsal region. The ulcerated areas were covered topically with dimethyl sulfoxide, KEM CON ONG, or KEM TRI BONG twice a day for 28 days. |