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Methylation of the first exon in the erythropoietin receptor gene does not correlate with its mRNA and protein level in cancer cells
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Erythropoietin receptor (EPOR) is a functional membrane-bound cytokine receptor. Erythropoietin (EPO) represents an important hematopoietic factor for production, maturation and differentiation of erythroid progenitors. In non-hematopoietic tissue, EPO/EPOR signalization could also play cytoprotective and antiapoptotic role. |