Đang chuẩn bị liên kết để tải về tài liệu:
Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome
Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Pseudogenes are gene copies presumed to mainly be functionless relics of evolution due to acquired deleterious mutations or transcriptional silencing. Using deep fulllength PacBio cDNA sequencing of normal human tissues and cancer cell lines, we identify here hundreds of novel transcribed pseudogenes expressed in tissue-specific patterns. |