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Hotspot mutation profiles of AKT1 in Asian women with breast and endometrial cancers

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The V-Akt murine thymoma viral oncogene (AKT) 1 (E17K) is a subfamily of serine/threonine protein kinases that affects the survival, proliferation, and invasion of cancer cells. The clinicopathological features and frequencies in Asian populations with AKT1 mutations in breast and endometrial cancers are unclear. |

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Hotspot mutation profiles of AKT1 in Asian women with breast and endometrial cancers