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Wound healing, calcium signaling, and other novel pathways are associated with the formation of butterfly eyespots

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One hypothesis surrounding the origin of novel traits is that they originate from the co-option of preexisting genes or larger gene regulatory networks into novel developmental contexts. Insights into a trait’s evolutionary origins can, thus, be gained via identification of the genes underlying trait development, and exploring whether those genes also function in other developmental contexts. Here we investigate the set of genes associated with the development of eyespot color patterns, a trait that originated once within the Nymphalid family of butterflies. Although several genes associated with eyespot development have been identified, the eyespot gene regulatory network remains largely unknown. |