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A Comprehensive Approach to Sequenceoriented IsomiR annotation (CASMIR): Demonstration with IsomiR profiling in colorectal neoplasia

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MicroRNA (miRNA) profiling is an important step in studying biological associations and identifying marker candidates. miRNA exists in isoforms, called isomiRs, which may exhibit distinct properties. With conventional profiling methods, limitations in assay and analysis platforms may compromise isomiR interrogation. |