Đang chuẩn bị liên kết để tải về tài liệu:
THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/ integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier

THO (Suppressors of the transcriptional defects of hpr1 delta by overexpression) complex 5 (THOC5), an mRNA export protein, is involved in the expression of only 1% of all genes. Using an interferon inducible knockout mouse system, we have previously shown that THOC5 is an essential element in the maintenance of hematopoietic stem cells and cytokine-mediated hematopoiesis in adult mice. |