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Differential contribution of p300 and CBP to regulatory element acetylation in mESCs

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The transcription coactivators CREB binding protein (CBP) and p300 are highly homologous acetyltransferases that mediate histone 3 lysine 27 acetylation (H3K27ac) at regulatory elements such as enhancers and promoters. |

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Differential contribution of p300 and CBP to regulatory element acetylation in mESCs