Đang chuẩn bị liên kết để tải về tài liệu:
Leptin differentially regulates chondrogenesis in mouse vertebral and tibial growth plates

Leptin plays an important role in mediating chondrogenesis of limb growth plate. Previous studies suggest that bone structures and development of spine and limb are different. The expression of Ob-Rb, the gene that encodes leptin receptors, is vertebral and appendicular region-specific, suggesting the regulation of leptin on VGP and TGP chondrogenesis may be very different. |