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Preparation of 18F-NaF radiopharmaceuticals using home-made automatic synthesis module at Hanoi Irradiation Center
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The aim of this study is to prepare 18F-NaF radiopharmaceutical using a home-made automatic synthesis module consisting of hardware and software which was made by a researcherteam of Hanoi Irradiation Center, HIC, Hanoi, Vietnam. Fluorine-18 isotopes produced in cyclotron KOTRON13 were transferred to the module and radioactive cation impurities were first removed by cation exchange on a carboxymethyl cation exchange (CM) cartridge, and then 18F - ion were trapped by a quaternary methyl ammonium anion exchange (QMA) cartridge. Finally, 18F - was eluated from the cartridge by isotonic saline water (NaCl 0,9% in water) in the form of 18F-NaF. |