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Mining differential top-k co-expression patterns from time course comparative gene expression datasets

Frequent pattern mining analysis applied on microarray dataset appears to be a promising strategy for identifying relationships between gene expression levels. Unfortunately, too many itemsets (co-expressed genes) are identified by this analysis method since it does not consider the importance of each gene within biological processes to a cellular response and does not take into account temporal properties under biological treatmentcontrol matched conditions in a microarray dataset. |