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Using ancestral information to detect and localize quantitative trait loci in genome-wide association studies

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In mammalian genetics, many quantitative traits, such as blood pressure, are thought to be influenced by specific genes, but are also affected by environmental factors, making the associated genes difficult to identify and locate from genetic data alone. In particular, the application of classical statistical methods to single nucleotide polymorphism (SNP) data collected in genome-wide association studies has been especially challenging. |

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Using ancestral information to detect and localize quantitative trait loci in genome-wide association studies