Đang chuẩn bị liên kết để tải về tài liệu:
AlloPred: Prediction of allosteric pockets on proteins using normal mode perturbation analysis

Despite being hugely important in biological processes, allostery is poorly understood and no universal mechanism has been discovered. Allosteric drugs are a largely unexplored prospect with many potential advantages over orthosteric drugs. Computational methods to predict allosteric sites on proteins are needed to aid the discovery of allosteric drugs, as well as to advance our fundamental understanding of allostery. |