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Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor - and extracellular matrix-induced signalling events in breast cancer progression

Cancer metastasis is the main contributor to breast cancer fatalities as women with the metastatic disease have poorer survival outcomes than women with localised breast cancers. There is an urgent need to develop appropriate prognostic methods to stratify patients based on the propensities of their cancers to metastasise. |