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Primary localized rectal/pararectal gastrointestinal stromal tumors: Results of surgical and multimodal therapy from the French Sarcoma group

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Rectal and pararectal gastrointestinal stromal tumors (GISTs) are rare. The optimal management strategy for primary localized GISTs remains poorly defined. Perioperative imatinib therapy was associated with improved disease-free survival. Preoperative imatinib was effective. Tumor shrinkage has a clear benefit for local excision in terms of feasibility and function preservation. |