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Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma

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New biomarkers are needed for the prognosis of advanced colorectal cancer, which remains incurable by conventional treatments. O6 -methylguanine DNA methyltransferase (MGMT) methylation and protein expression have been related to colorectal cancer treatment failure and tumor progression. |