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Prognostic influence of cyclooxygenase-2 protein and mRNA expression in node-negative breast cancer patients

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Cyclooxygenases (COX) play a key role in prostaglandin metabolism and are important for tumor development and progression. The aim of this study was to analyze the prognostic impact of COX-2 expression in a cohort of lymph node-negative breast cancer patients not treated in the adjuvant setting. |