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CXCL12 expression promotes esophageal squamous cell carcinoma proliferation and worsens the prognosis

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The chemokine CXCL12 and its corresponding receptor CXCR4 are key players in the development of several cancers. Therefore, we hypothesized that there is a functional causality between CXCL12 expression and tumor progression in patients with esophageal squamous cell carcinoma (ESCC). |